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1

Tropism-Modification Strategies for Targeted Gene Delivery Using Adenoviral Vectors

Coughlan, Lynda, Alba, Raul, Parker, Alan L., Bradshaw, Angela C., McNeish, Iain A., Nicklin, Stuart A., Baker, Andrew H.

Journal:

Year:

2010

Language:

english

File:

PDF, 2.09 MB

english, 2010

2

RUNX1: an emerging therapeutic target for cardiovascular disease

Riddell, Alexandra, McBride, Martin, Braun, Thomas, Nicklin, Stuart A, Cameron, Ewan, Loughrey, Christopher M, Martin, Tamara P

Journal:

Cardiovascular Research

Year:

2020

File:

PDF, 936 KB

2020

3

Mouse adenovirus type 1 and human adenovirus type 5 differ in endothelial cell tropism and liver targeting

Liesbeth Lenaerts, John H. McVey, Andrew H. Baker, Laura Denby, Stuart Nicklin, Erik Verbeken, Lieve Naesens

Journal:

The Journal of Gene Medicine

Year:

2009

Language:

english

File:

PDF, 184 KB

english, 2009

4

In vitro and in vivo characterisation of endothelial cell selective adenoviral vectors

Stuart A. Nicklin, Steve J. White, Campbell G. Nicol, Dan J. Von Seggern, Andrew H. Baker

Journal:

The Journal of Gene Medicine

Year:

2004

Language:

english

File:

PDF, 300 KB

english, 2004

5

Targeting gene therapy vectors to the vascular endothelium

Lorraine M. Work, Stuart A. Nicklin, Andrew H. Baker

Journal:

Current Atherosclerosis Reports

Year:

2003

Language:

english

File:

PDF, 654 KB

english, 2003

6

J. Zhang and G. Rokosh (eds): Cardiac Gene Expression, Methods in Molecular Biology Series, Vol. 366

Journal:

Molecular Biotechnology

Year:

2007

Language:

english

File:

PDF, 79 KB

english, 2007

7

10.1038/nbt0901-838

Reynolds, Paul N., Nicklin, Stuart A., Kaliberova, Lioudmila, Boatman, Brian G., Grizzle, William E., Balyasnikova, Irina V., Baker, Andrew H., Danilov, Sergei M., Curiel, David T.

Journal:

Nature Biotechnology

Year:

2001

Language:

english

File:

PDF, 2.65 MB

english, 2001

8

Cell-selective viral gene delivery vectors for the vasculature

Andrew H. Baker, Angelika Kritz, Lorraine M. Work, Stuart A. Nicklin

Journal:

Experimental Physiology

Year:

2005

Language:

english

File:

PDF, 120 KB

english, 2005

9

Biodistribution and inflammatory profiles of novel penton and hexon double-mutant serotype 5 adenoviruses

Angela C. Bradshaw, Lynda Coughlan, Ashley M. Miller, Raul Alba, Nico van Rooijen, Stuart A. Nicklin, Andrew H. Baker

Journal:

Journal of Controlled Release

Year:

2012

Language:

english

File:

PDF, 2.75 MB

english, 2012

10

Use of in vivo phage display to engineer novel adenoviruses for targeted delivery to the cardiac vasculature

Campbell G. Nicol, Laura Denby, Oscar Lopez-Franco, Rachel Masson, Crawford A. Halliday, Stuart A. Nicklin, Angelika Kritz, Lorraine M. Work, Andrew H. Baker

Journal:

Year:

2009

Language:

english

File:

PDF, 506 KB

english, 2009

11

Transductional and transcriptional targeting of cancer cells using genetically engineered viral vectors

Stuart A. Nicklin, Kate L. Dishart, Hildegard Buening, Paul N. Reynolds, Michael Hallek, Glen R. Nemerow, Dan J. Von Seggern, Andrew H. Baker

Journal:

Year:

2003

Language:

english

File:

PDF, 549 KB

english, 2003

12

Third-generation lentivirus vectors efficiently transduce and phenotypically modify vascular cells: implications for gene therapy

Kate L Dishart, Laura Denby, Sarah J George, Stuart A Nicklin, Satya Yendluri, Melanie J Tuerk, Michael P Kelley, Brian A Donahue, Andrew C Newby, Thomas Harding, Andrew H Baker

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2003

Language:

english

File:

PDF, 531 KB

english, 2003

13

Prevention of coronary in-stent restenosis and vein graft failure: Does vascular gene therapy have a role?

Keith E. Robertson, Robert A. McDonald, Keith G. Oldroyd, Stuart A. Nicklin, Andrew H. Baker

Journal:

Pharmacology & Therapeutics

Year:

2012

Language:

english

File:

PDF, 403 KB

english, 2012

14

Regulation of cardiovascular remodeling by the counter-regulatory axis of the renin–angiotensin system

Clarke, Carolyn, Flores-Muñoz, Monica, McKinney, Clare A, Milligan, Graeme, Nicklin, Stuart A

Journal:

Future Cardiology

Year:

2013

Language:

english

File:

PDF, 2.77 MB

english, 2013

15

Ad5:Ad48 Hexon Hypervariable Region Substitutions Lead to Toxicity and Increased Inflammatory Responses Following Intravenous Delivery

Coughlan, Lynda, Bradshaw, Angela C, Parker, Alan L, Robinson, Hollie, White, Katie, Custers, Jerome, Goudsmit, Jaap, Van Roijen, Nico, Barouch, Dan H, Nicklin, Stuart A, Baker, Andrew H

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 2.07 MB

english, 2012

16

FX and Host Defense Evasion Tactics by Adenovirus

Baker, Andrew H, Nicklin, Stuart A, Shayakhmetov, Dmitry M

Journal:

Molecular Therapy

Year:

2013

Language:

english

File:

PDF, 498 KB

english, 2013

17

Novel vectors for in vivo gene delivery to vascular tissue

White, Kathryn, Nicklin, Stuart A, Baker, Andrew H

Journal:

Expert Opinion on Biological Therapy

Year:

2007

Language:

english

File:

PDF, 610 KB

english, 2007

18

Enhanced gene transfer activity of peptide-targeted gene-delivery vectors

Parker, Alan L., Fisher, Kerry D., Oupicky, David, Read, Martin L., Nicklin, Stuart A., Baker, Andrew H., Seymour, Leonard W.

Journal:

Journal of Drug Targeting

Year:

2005

Language:

english

File:

PDF, 572 KB

english, 2005

19

The importance of coagulation factors binding to adenovirus: historical perspectives and implications for gene delivery

Lopez-Gordo, Estrella, Denby, Laura, Nicklin, Stuart A, Baker, Andrew H

Journal:

Expert Opinion on Drug Delivery

Year:

2014

Language:

english

File:

PDF, 1.12 MB

english, 2014

20

Adenoviral Serotype 5 Vectors Pseudotyped with Fibers from Subgroup D Show Modified Tropism In Vitro and In Vivo

Denby, Laura, Work, Lorraine M., Graham, Delyth, Hsu, Catherine, Von Seggern, Dan J., Nicklin, Stuart A., Baker, Andrew H.

Journal:

Human Gene Therapy

Year:

2004

Language:

english

File:

PDF, 183 KB

english, 2004

21

25. Development and Characterization of Viral Vectors with High Specificity for Atherosclerotic Plaques

White, Katie M., Buening, Hildergard, Work, Lorraine M., Hallek, Michael, Nicklin, Stuart A., Baker, Andrew H.

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 90 KB

english, 2006

22

376. Hepatic Tropism of Adenoviral Type 5 Vectors Can Be Mediated by Multiple Coagulation Factors

Parker, Alan L., Nicol, Campbell G., Waddington, Simon N., Buckley, Suzanne M., Shayakhmetov, Dmitry M., Ni, Shaoheng H., Lieber, Andre, McVey, John H., Denby, Laura, Nicklin, Stuart A., Baker, Andrew

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 90 KB

english, 2006

23

21. Peptide-Targeted Ad19p-Based Adenoviral Vectors for Renal Gene Delivery

Denby, Laura, Work, Lorraine M., Von Seggern, Dan J., Wu, Eugene, Hunt, Ela, Nicklin, Stuart A., Baker, Andrew H.

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 91 KB

english, 2006

24

Combined therapeutic benefit of mitochondria-targeted antioxidant, MitoQ10, and angiotensin receptor blocker, losartan, on cardiovascular function

McLachlan, Jennifer, Beattie, Elisabeth, Murphy, Michael P., Koh-Tan, Caline H.H., Olson, Erin, Beattie, Wendy, Dominiczak, Anna F., Nicklin, Stuart A., Graham, Delyth

Journal:

Journal of Hypertension

Year:

2014

Language:

english

File:

PDF, 14.71 MB

english, 2014

25

Special Focus Issue on the Annual Meeting of the British Society for Gene and Cell Therapy

Nicklin, Stuart A., Griesenbach, Uta, Baker, Andrew H.

Journal:

Human Gene Therapy

Year:

2015

Language:

english

File:

PDF, 48 KB

english, 2015

26

Electrical consequences of cardiac myocyte: fibroblast coupling

McArthur, Lisa, Chilton, Lisa, Smith, Godfrey L., Nicklin, Stuart A.

Journal:

Biochemical Society Transactions

Year:

2015

Language:

english

File:

PDF, 508 KB

english, 2015

27

G protein-coupled receptor 35: an emerging target in inflammatory and cardiovascular disease

Divorty, Nina, Mackenzie, Amanda E., Nicklin, Stuart A., Milligan, Graeme

Journal:

Frontiers in Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.41 MB

english, 2015

28

Manipulating Adenovirus Hexon Hypervariable Loops Dictates Immune Neutralisation and Coagulation Factor X-dependent Cell Interaction In Vitro and In Vivo

Ma, Jiangtao, Duffy, Margaret R., Deng, Lin, Dakin, Rachel S., Uil, Taco, Custers, Jerome, Kelly, Sharon M., McVey, John H., Nicklin, Stuart A., Baker, Andrew H., Falck-Pedersen, Erik

Journal:

Year:

2015

Language:

english

File:

PDF, 3.48 MB

english, 2015

29

Requirements for Receptor Engagement during Infection by Adenovirus Complexed with Blood Coagulation Factor X

Bradshaw, Angela C., Parker, Alan L., Duffy, Margaret R., Coughlan, Lynda, van Rooijen, Nico, Kähäri, Veli-Matti, Nicklin, Stuart A., Baker, Andrew H., Imperiale, Michael J.

Journal:

Year:

2010

Language:

english

File:

PDF, 11.17 MB

english, 2010

30

Angiotensin-(1–7) and angiotensin-(1–9): function in cardiac and vascular remodelling

McKinney, Clare A., Fattah, Caroline, Loughrey, Christopher M., Milligan, Graeme, Nicklin, Stuart A.

Journal:

Clinical Science

Year:

2014

Language:

english

File:

PDF, 499 KB

english, 2014

31

Efficient Transduction of Primary Vascular Cells by the Rare Adenovirus Serotype 49 Vector

Dakin, Rachel S., Parker, Alan L., Delles, Christian, Nicklin, Stuart A., Baker, Andrew H.

Journal:

Human Gene Therapy

Year:

2015

Language:

english

File:

PDF, 560 KB

english, 2015

32

Development of Renal-targeted Vectors Through Combined In Vivo Phage Display and Capsid Engineering of Adenoviral Fibers From Serotype 19p

Denby, Laura, Work, Lorraine M, Seggern, Dan J Von, Wu, Eugene, McVey, John H, Nicklin, Stuart A, Baker, Andrew H

Journal:

Molecular Therapy

Year:

2007

Language:

english

File:

PDF, 585 KB

english, 2007

33

Efficient Vascular Endothelial Gene Transfer Following Intravenous Adenovirus Delivery

Nicklin, Stuart A, Baker, Andrew H

Journal:

Molecular Therapy

Year:

2008

Language:

english

File:

PDF, 227 KB

english, 2008

34

Influence of Coagulation Factor X on In Vitro and In Vivo Gene Delivery by Adenovirus (Ad) 5, Ad35, and Chimeric Ad5/Ad35 Vectors

Greig, Jenny A, Buckley, Suzanne MK, Waddington, Simon N, Parker, Alan L, Bhella, David, Pink, Rebecca, Rahim, Ahad A, Morita, Takashi, Nicklin, Stuart A, McVey, John H, Baker, Andrew H

Journal:

Molecular Therapy

Year:

2009

Language:

english

File:

PDF, 641 KB

english, 2009

35

Adenovirus 5 Fibers Mutated at the Putative HSPG-binding Site Show Restricted Retargeting with Targeting Peptides in the HI Loop

Kritz, Angelika B, Nicol, Campbell G, Dishart, Kate L, Nelson, Ruth, Holbeck, Susan, Von Seggern, Dan J, Work, Lorraine M, McVey, John H, Nicklin, Stuart A, Baker, Andrew H

Journal:

Molecular Therapy

Year:

2007

Language:

english

File:

PDF, 515 KB

english, 2007

36

G-Protein-Coupled Receptor 35 Mediates Human Saphenous Vein Vascular Smooth Muscle Cell Migration and Endothelial Cell Proliferation

McCallum, Jennifer E., Mackenzie, Amanda E., Divorty, Nina, Clarke, Carolyn, Delles, Christian, Milligan, Graeme, Nicklin, Stuart A.

Journal:

Journal of Vascular Research

Year:

2016

Language:

english

File:

PDF, 385 KB

english, 2016

37

Tropism-Modified Adenoviral and Adeno-Associated Viral Vectors for Gene Therapy

Nicklin, Stuart, Baker, Andrew

Journal:

Current Gene Therapy

Year:

2002

Language:

english

File:

PDF, 249 KB

english, 2002

38

SPIE Proceedings [SPIE Aerospace/Defense Sensing, Simulation, and Controls - Orlando, FL (Monday 16 April 2001)] Thermosense XXIII - Night vision: changing the way we drive

Klapper, Stuart H., Kyle, Robert J. S., Nicklin, Robert L., Kormos, Alexander L., Rozlosnik, Andres E., Dinwiddie, Ralph B.

Year:

2001

Language:

english

File:

PDF, 1.07 MB

english, 2001

39

A Novel Mechanism of Action for Angiotensin-(1–7) via the Angiotensin Type 1 Receptor

Nicklin, Stuart A.

Journal:

Year:

2016

Language:

english

File:

PDF, 386 KB

english, 2016

40

Defining a novel role for the coxsackie and adenovirus receptor in human adenovirus serotype 5 transduction in vitro in the presence of mouse serum

Lopez-Gordo, Estrella, Doszpoly, Andor, Duffy, Margaret R., Coughlan, Lynda, Bradshaw, Angela C., White, Katie M., Denby, Laura, Nicklin, Stuart A., Baker, Andrew H.

Journal:

Journal of Virology

Year:

2017

Language:

english

File:

PDF, 2.88 MB

english, 2017

41

The Orphan Receptor GPR35 Contributes to Angiotensin II–Induced Hypertension and Cardiac Dysfunction in Mice

Divorty, Nina, Milligan, Graeme, Graham, Delyth, Nicklin, Stuart A

Journal:

American Journal of Hypertension

Year:

2018

Language:

english

File:

PDF, 1.05 MB

english, 2018

42

Utilizing proteomics to understand and define hypertension: where are we and where do we go?

Delles, Christian, Carrick, Emma, Graham, Delyth, Nicklin, Stuart A.

Journal:

Expert Review of Proteomics

Year:

2018

Language:

english

File:

PDF, 1.71 MB

english, 2018

43

What matters in Cardiovascular Research? Scientific discovery driving clinical delivery

Guzik, Tomasz J, Antoniades, Charalambos, Baker, Andrew H, Harrison, David G, Loughrey, Christopher M, Maffia, Pasquale, Murphy, Elizabeth, Nicklin, Stuart A, Peter, Karlheinz, Pearson, Jeremy, Casade

Journal:

Cardiovascular Research

Year:

2018

Language:

english

File:

PDF, 228 KB

english, 2018

44

Human Adenovirus Serotype 5 Is Sensitive to IgM-Independent Neutralization In Vitro and In Vivo

Doszpoly, Andor, de la Cuesta, Fernando, Lopez-Gordo, Estrella, Bénézech, Cécile, Nicklin, Stuart A., Baker, Andrew H.

Journal:

Year:

2019

Language:

english

File:

PDF, 3.67 MB

english, 2019

45

Human Adenovirus Serotype 5 Is Sensitive to IgM-Independent Neutralization In Vitro and In Vivo

Doszpoly, Andor, de la Cuesta, Fernando, Lopez-Gordo, Estrella, Bénézech, Cécile, Nicklin, Stuart A., Baker, Andrew H.

Journal:

Year:

2019

File:

PDF, 3.67 MB

2019

46

Regulation of connexin 43 by interleukin 1β in adult rat cardiac fibroblasts and effects in an adult rat cardiac myocyte: fibroblast co-culture model

McArthur, Lisa, Riddell, Alexandra, Chilton, Lisa, Smith, Godfrey L., Nicklin, Stuart A.

Journal:

Year:

2020

Language:

english

File:

PDF, 2.51 MB

english, 2020

47

Regulation of connexin 43 by interleukin 1β in adult rat cardiac fibroblasts and effects in an adult rat cardiac myocyte: fibroblast co-culture model

McArthur, Lisa, Riddell, Alexandra, Chilton, Lisa, Smith, Godfrey L., Nicklin, Stuart A.

Journal:

Year:

2020

File:

PDF, 2.51 MB

2020

48

Signalling pathways linking cysteine cathepsins to adverse cardiac remodelling

O'Toole, Dylan, Zaeri, Ali Abdullah I., Nicklin, Stuart A., French, Anne T., Loughrey, Christopher M., Martin, Tamara P.

Journal:

Cellular Signalling

Year:

2020

File:

PDF, 6.63 MB

2020

49

[BMJ Publishing Group Ltd and British Cardiovascular Society British Cardiovascular Society Annual Conference âDigital Health Revolutionâ 3â5 June 2019 - ()] Basic Science - BS7âAngiotensin-(1â9) inhibits neointima formation in a murine vein graft model and modulates ERK1/2 phosphorylation and microRNA-132 pathways in human vascular smooth muscle cells

Robertson, Stacy, Nicklin, Stuart, McKinney, Clare, McArthur, Lisa, Delles, Christian, Milligan, Graeme, Kennedy, Simon, Baker, Andrew

Year:

2019

File:

PDF, 678 KB

2019

50

[BMJ Publishing Group Ltd and British Cardiovascular Society The Scottish Cardiovascular Forum 2018, 3rd February 2018, Trinity Biomedical Science Institute, Trinity College Dublin Ireland - ()] Oral Presentations - 9âInvestigating the counter regulatory renin angiotensin system axis in the stroke prone spontaneously hypertensive rat in ischaemic stroke

McFall, Aisling, Zentilin, Lorena, Giacca, Mauro, Nicklin, Stuart A, Work, Lorraine M

File:

PDF, 53 KB

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